Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX‑1 in apoE<sup>‑/‑</sup> mice
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چکیده
منابع مشابه
Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation
Studying the role of a particular gene in atherosclerosis typically requires a time-consuming and often difficult process of generating double knockouts or transgenics on ApoE-/- or LDL receptor (LDLR)-/- background. Recently, it was reported that adeno-associated-virus-8 (AAV8)-mediated overexpression of PCSK9 (AAV8-PCSK9) rapidly induced hyperlipidemia. However, using this method in C57BL6 wi...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2020
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2020.9457